Telecytologic diagnosis of cervical smears for triage of self-sampled human papillomavirus–positive women in a resource-limited setting: concept development before implementation

Vassilakos, PierreClarke, HollyMurtas, MicolStegmüller, Thomas GrégoireWisniak, AniaAkhoundova, FaridaSando, ZacharieOrock, George EnowSormani, JessicaThiran, Jean-PhilippePetignat, PatrickStegmüller, ThomasThiran, Jean-Philippe2023-08-172023-08-172023-08-17202310.1016/j.jasc.2023.02.001https://infoscience.epfl.ch/handle/20.500.14299/199930Cytology is an option for triaging human papillomavirus (HPV)-positive women. The interpretation of cytologic slides requires expertise and financial resources that are not always available in resource-limited settings. A solution could be offered by manual preparation and digitization of slides on site for real-time remote cytologic diagnosis by specialists. In the present study, we evaluated the operational feasibility and cost of manual preparation and digitization of thin-layer slides and the diagnostic accuracy of screening with virtual microscopy.Cervical cancerCytologyDiagnostic imagingPreventionTelepathologyTelecytologic diagnosis of cervical smears for triage of self-sampled human papillomavirus–positive women in a resource-limited setting: concept development before implementationtext::journal::journal article::research article