Sinisi, RiccardoMorales Morales, Alma RosaDubikovskaya, Elena ADhaka, Rajendra Singh2019-12-052019-12-052019-12-052018https://infoscience.epfl.ch/handle/20.500.14299/163734The application provides fluorescent dyes, which are cyanine dyes that incorporate additional aza moieties in the indolenium heterocycles and/or in the methine chains connecting them. Symmetrical and unsymmetrical chemically reactive azacyanine dyes are described for conjugation, as well as their bioconjugates for in-vitro and in-vivo assays and fluorescence imaging.patentUS201807990659930375