A Time-Gated 128x128 CMOS SPAD Array for on-Chip Fluorescence Detection

Maruyama, YukiCharbon, Edoardo2012-06-122012-06-122012-06-122011https://infoscience.epfl.ch/handle/20.500.14299/81720An all-digital, time-gated 128x128 CMOS image sensor for on-chip fluorescence detection is presented. The sensor pixel consists of a single-photon avalanche diode (SPAD), time gating circuitry and a 1bit memory. The sensor allows on-chip fluorescence detection and fluorescence lifetime imaging microscopy (FLIM) for on-chip molecular detection such as DNA, protein and cancer markers.A Time-Gated 128x128 CMOS SPAD Array for on-Chip Fluorescence Detectiontext::conference output::conference proceedings::conference paper