Takahashi-Umebayashi, MiwaPineau, LudovicHannich, ThomasZumbuehl, AndreasDoval, David AlonsoMatile, StefanHeinis, ChristianTurcatti, GerardoLoewith, RobbieRoux, AurelienReymond, LucJohnsson, KaiRiezman, Howard2012-06-252012-06-252012-06-25201110.2533/chimia.2011.849https://infoscience.epfl.ch/handle/20.500.14299/82332WOS:000298362000006The study of membranes is at a turning point. New theories about membrane structure and function have recently been proposed, however, new technologies, combining chemical, physical, and biochemical approaches are necessary to test these hypotheses. In particular, the NCCR in chemical biology aims to visualize and characterize membrane microdomains and determine their function during hormone signaling.Chemical biologyFluorescent dyesGiant unilamellar vesiclesInsulin receptorMembranesMicrodomainsRaftsSignalingSphingolipidsSterolsGpi-Anchored ProteinsNeuropathy Type-ISphingolipidsMutationsSubunitDomainstext::journal::journal article::research article