Jaegli, StephanieVors, Jean-PierreNeuville, LucZhu, Jieping2010-11-252010-11-252010-11-25201010.1016/j.tet.2010.09.056https://infoscience.epfl.ch/handle/20.500.14299/585953'-Alkyl-3-cyanomethyloxindoles, prepd. by a palladium-catalyzed domino Heck/cyanation, were efficiently converted to spiropyrrolidinyl-, spiropiperidinyl- and spirocyclopropyl-oxindoles. The so-obtained spirooxindoles bearing three diversity points were further functionalized via selective N-acylation, N-alkylation, N-sulfonylation, SNAr reaction and Buchwald-Hartwig N-arylation reaction to reach diverse set of heterocycles. [on SciFinder (R)]text::journal::journal article::research article