Copper-Catalyzed Alkylation of Benzoxazoles with Secondary Alkyl Halides

Ren, PengSalihu, IsufScopelliti, RosarioHu, Xile2012-03-122012-03-122012-03-12201210.1021/ol300348whttps://infoscience.epfl.ch/handle/20.500.14299/78676WOS:000302387800023Copper-catalyzed direct alkylation of benzoxazoles using nonactivated secondary alkyl halides has been developed. The best catalyst is a new copper(I) complex (1), and the reactions are promoted by bis[2-(N,N-dimethylamino)ethyl] ether.Carbon-Hydrogen BondsNickel Pincer ComplexC-H BondsDirect AlkynylationGrignard-ReagentsDirect FunctionalizationDirect ArylationCross-CouplingsPalladiumBromidesCopper-Catalyzed Alkylation of Benzoxazoles with Secondary Alkyl Halidestext::journal::journal article::research article