Soares, Ana FranciscaLei, HongxiaPreitner, FrédéricThorens, BernardGruetter, Rolf2014-11-182014-11-182014-11-182014https://infoscience.epfl.ch/handle/20.500.14299/108940We performed 1H MRS at 14.1T in the liver of GLUT2-/- and wild-type (WT) mice. Improved spectral resolution allowed identifying peaks from the lipid resonances, choline containing compounds, taurine and glycogen in WT mice. Performing the same measurements in GLUT2-/- mice revealed a strong contribution from carbohydrates, notably glucose, to the 1H MR liver spectrum. Also a reduced lipid content was detected by 1H MRS in those mice. The characterization of the hepatic profile by 1H MRS in GLUT2-/- mice is of great value to address changes in the main energy fuels in the liver longitudinally.MRSCIBM-AITtext::conference output::conference poster not in proceedings