Polet, DamienAlexakis, AlexandreTissot-Croset, KarineCorminboeuf, ClemenceDitrich, Klaus2007-10-222007-10-222007-10-22200610.1002/chem.200501180https://infoscience.epfl.ch/handle/20.500.14299/13201A new phosphoramidite ligand was used in the iridium-catalyzed allylic substitution reaction. This permitted high regio- and enantioselectivity on a wide variety of substrates and nucleophiles. Because of the stereospecificity of the reaction obtained by using branched substrates, a kinetic resoln. reaction was attempted. The origin of the impressive efficiency of this ligand in terms of kinetics was explored in detail, as was the role of the substituent in the ortho-position of the amine moiety. [on SciFinder (R)]Amination kinetics (iridium-catalyzed stereoselective allylic amination reaction using phosphoramidite derivs. as ligands); Density functional theory (iridium-catalyzed stereoselective allylic substitution reaction using chiral NN-[(aryl)ethyl]dinaphtho[21-d:1'2'-f][132]dioxaphosphepin-4-amine (phosphoramidite) ligand and related study of d. functional theory model); Amination (regioselective; iridium-catalyzed stereoselective allylic amination reaction using phosphoramidite derivs. as ligands); Amination; Amination catalysts (stereoselective; iridium-catalyzed stereoselective allylic amination reaction using phosphoramidite derivs. as ligands)iridium stereoselective allylic substitution phosphoramidite ligand; allylic substitution asym catalysis chiral ligand iridium phosphoramiditetext::journal::journal article::research article