Heinis, Christian2023-06-052023-06-052023-06-052023-05-0810.1038/s41589-023-01329-yhttps://infoscience.epfl.ch/handle/20.500.14299/197901WOS:000983888400001Tricyclic peptides have reduced conformational flexibility, making them well suited for ligand development. Researchers have now generated large combinatorial libraries of tricyclic peptides using a disulfide-directing motif. Screening these libraries discovered binders to challenging protein targets.Biochemistry & Molecular Biologytext::journal::journal article::research article