Wang, Shi-XinWang, Mei-XiangWang, De-XianZhu, Jieping2010-11-252010-11-252010-11-25200810.1002/anie.200704315https://infoscience.epfl.ch/handle/20.500.14299/58412A [(salen)-AlIIICl] complex catalyzes the Passerini three-component reaction of an aldehyde, a carboxylic acid, and an isocyanide to afford alpha -acyloxyamides, e.g., I, with good to excellent enantioselectivity. A variety of nonchelating substrates can be used to generate the versatile chiral products. [on SciFinder (R)]Amides Role: SPN (Synthetic preparation)PREP (Preparation) (acyloxy-; stereoselective prepn. of alpha -acyloxyamides via salen/Lewis acid-catalyzed Passerini three-component reaction of aldehydesisocyanidesand carboxylic acids); Addition reaction catalysts; Stereoselective synthesis (stereoselective prepn. of alpha -acyloxyamides via salen/Lewis acid-catalyzed Passerini three-component reaction of aldehydesisocyanidesand carboxylic acids); Aldehydes; Carboxylic acids; Isocyanides Role: RCT (Reactant)RACT (Reactant or reagent) (stereoselective prepn. of alpha -acyloxyamides via salen/Lewis acid-catalyzed Passerini three-component reaction of aldehydesisocyanidesand carboxylic acids); Passerini reaction (stereoselective; stereoselective prepn. of alpha -acyloxyamides via salen/Lewis acid-catalyzed Passerini three-component reaction of aldehydesisocyanidesand carboxylic acids)aldehyde isocyanide carboxylic acid salen Passerini three component reaction; amide alpha acyloxy stereoselective prepntext::journal::journal article::research article