Ren, WeiwuTappin, NicholasWang, QianZhu, Jieping2013-09-142013-09-142013-09-14201310.1055/s-0033-1339472https://infoscience.epfl.ch/handle/20.500.14299/94652WOS:000325540000012A synthetic approach featuring a key intramolecular oxidative coupling of a dianion for the formation of the C7–C16 bond was exploited aiming at the synthesis of strictamine. Treatment of substituted tetrahydrocarboline with LHMDS at –78 °C followed by iodine at room temperature afforded a tetracyclic compound, a substructure of eburnane-type alkaloid, via the formation of the Na–C16 bond.strictamineoxidative couplingindole alkaloidtetrahydro- β-carbolineSynthetic Study towards Strictamine: The Oxidative Coupling Approachtext::journal::journal article::research article