Drouet, FleurLalli, ClaudiaLiu, HuaMasson, GeraldineZhu, Jieping2011-02-172011-02-172011-02-17201110.1021/ol102625shttps://infoscience.epfl.ch/handle/20.500.14299/64466WOS:000285728000025Highly enantioselective direct amination of enamides catalyzed by chiral nonracemic calcium bis(phosphate) complex 3g afforded optically active 1,2-hydrazinoimines 4. Following a subsequent in situ hydrolysis or reduction, 2-hydrazinoketones 5 or syn-1,2-disubstituted 1,2- diamines 6 were obtained in high yields and excellent enantiomeric excess.Asymmetric Alpha-AminationTransition-Metal CatalysisBond-Forming ReactionsBronsted Acid CatalysisStereoselective C-CEne-Type ReactionPhosphoric-AcidReductive AminationCarbonyl-CompoundsAmino-AcidsChiral Calcium Organophosphate-Catalyzed Enantioselective Electrophilic Amination of Enamidestext::journal::journal article::research article