Cosson, SteffenAeberli, Luc G.Brandenberg, NathalieLutolf, Matthias P.2015-02-202015-02-202015-02-20201510.1039/c4lc00848khttps://infoscience.epfl.ch/handle/20.500.14299/111355WOS:000346478100010The fabrication of microfluidic devices is often still a time-consuming and costly process. Here we introduce a very simple and cheap microfabrication process based on "razor writing", also termed xurography, for the ultra-rapid prototyping of microfluidic devices. Thin poly(dimethylsiloxane) (PDMS) membranes are spin-coated on flexible plastic foil and cut into user-defined shapes with a bench-top cutter plotter. The PDMS membranes can then be assembled into desirable microdevices via plasma bonding. The plastic foil allows manipulation of exceptionally thin (30-300 mu m) PDMS layers and can be readily peeled after fabrication. This versatile technique can be used to produce a wide variety of microfluidic device prototypes within just a few hours.text::journal::journal article::research article