Confinement of a tris-aqua Gd(III) complex in silica nanoparticles leads to high stability and high relaxivity and supresses anion binding

Karimdjy, Maria MoulaTallec, GaylordFries, Pascal H.Imbert, DanielMazzanti, Marinella2015-05-292015-05-292015-05-29201510.1039/c5cc01352fhttps://infoscience.epfl.ch/handle/20.500.14299/114769WOS:000352270100031The water soluble tris-aqua complex [Gd(dhqN-SO3)(H2O)(3)](3-) based on a hexadentate hydroxyquinoline ligand shows high thermodynamic stability and high relaxivity (12.54 mM(-1) s(-1) at 1.2 T). Its non-covalent confinement in 25 nm silica nanoparticles prevents transmetallation and endogenous anion binding and leads to higher relaxivity over a wide range of magnetic fields.Confinement of a tris-aqua Gd(III) complex in silica nanoparticles leads to high stability and high relaxivity and supresses anion bindingtext::journal::journal article::research article