Stradolini, FrancescaTuoheti, AbuduwailiKilic, TugbaDemarchi, DaniloCarrara, Sandro2018-12-132018-12-132018-12-132018-09-0110.1016/j.vlsi.2018.04.004https://infoscience.epfl.ch/handle/20.500.14299/152442WOS:000448094300022Induction of anesthesia with propofol is a largely adopted technique in hospital environments. The correct dosage of this compound is essential to avoid under- or over-anesthesia that may result in serious side-effects. Therefore, in clinical settings, long-term monitoring of propofol is of great importance. To this aim, in this work, we present the design and the validation of a custom-made, low-cost and portable Point-of-Care (PoC) system based on electrochemical detection for propofol monitoring. Fouling phenomenon due to phenolic oxidation of propofol has been overcome by adopting a Pencil Graphite Electrode (PGE) 3H as sensor. The validation of the system focused on testing the measurement speed through scan-rate analysis, which is important due to the fast clearance of propofol; and interference study with Paracetamol(APAP), since it is an analgesic compound frequently administered with propofol in medical practices.Computer Science, Hardware & ArchitectureEngineering, Electrical & ElectronicComputer ScienceEngineering2,6-diisopropylphenol propofolphenolic-compoundsmass-spectrometryelectrodeanesthesiabloodcaretext::journal::journal article::research article