Feige, Jerome N.Gerber, AlanCasals-Casas, CristinaYang, QianWinkler, CarineBedu, ElodieBueno, ManuelGelman, LaurentAuwerx, JohanGonzalez, Frank J.Desvergne, Beatrice2011-12-162011-12-162011-12-16201010.1289/ehp.0901217https://infoscience.epfl.ch/handle/20.500.14299/75733WOS:000274482400024BACKGROUND: The modulation of energetic homeostasis by pollutants has recently emerged as a potential contributor to the onset of metabolic disorders. Diethylhexyl phthalate (DEHP) is a widely used industrial plasticizer to which humans are widely exposed. Phthalates can activate the three peroxisome proliferator-activated receptor (PPAR) isotypes on cellular models and induce peroxisome proliferation in rodents.Dehpendocrine disruptormetabolismPparspecies specificityActivated-Receptor-AlphaEndocrine DisruptorsObesity EpidemicHepatocellular ProliferationWaist CircumferenceOrganotin CompoundsHuman RiskGammaLiverDi(2-Ethylhexyl)PhthalateThe Pollutant Diethylhexyl Phthalate Regulates Hepatic Energy Metabolism via Species-Specific PPAR alpha-Dependent Mechanismstext::journal::journal article::research article