Reinmueller, ViktoriaZhu, Jieping2017-10-012017-10-012017-10-012017https://infoscience.epfl.ch/handle/20.500.14299/140914The present invention relates to the use for enhancing Notch signaling in an individual, of a compound showing the general formula (I) and/or a pharmaceutically acceptable salt or ester thereof, for the treatment of a disease selected from the group of dermatological disorders including atopic dermatitis, psoriasis, immune related disorders, cancer, squamous cell carcinoma, cutaneous and lung squamous cell carcinoma, head and neck cancer, non-melanoma skin cancer, basal cell carcinoma and actinic keratosis, neuroendocrine tumors, neuroendocrine small cell carcinoma and carcinoid tumors, thyroid carcinomas, muscular disorders muscular dystrophy and impaired regeneration capacity after injury; use in immunotherapy for cancer.Enhancers of notch signaling and their use in the treatment of cancers and malignancies medicable by upregulation of notchpatentJP7402300JP2023027160JP2023002688AU2017232391AU2022228099AU2017232391US2020360355US10772876JP2019513703US2019083476EP3429576AU2017232391WO201715819055628769