De Nanteuil, FlorianSerrano, EloisaPerrotta, DanieleWaser, Jerome2014-06-162014-06-162014-06-16201410.1021/ja5024578https://infoscience.epfl.ch/handle/20.500.14299/104331WOS:000335369200023We report the first example of a dynamic kinetic asymmetric [3 + 2] annulation reaction of aminocyclopropanes with both enol ethers and aldehydes. Using a Cu catalyst and a commercially available bisoxazoline ligand, cyclopentyl- and tetrahydrofurylamines were obtained in 69-99% yield and up to a 98:2 enantiomeric ratio using the same reaction conditions. The method gives access to important enantio-enriched nitrogen building blocks for the synthesis of bioactive compounds.text::journal::journal article::research article