Novel DOTA-based prochelator for divalent peptide vectorization: synthesis of dimeric bombesin analogues for multimodality tumor imaging and therapy

Keelara, AbirajJaccard, HuguesKretzschmar, M.Helm, LotharMaecke, Helmuth R.2008-09-182008-09-18200810.1039/b805281fhttps://infoscience.epfl.ch/handle/20.500.14299/27984WOS:00025755270000512698Dimeric peptidic vectors, obtained by the divalent grafting of bombesin analogues on a newly synthesized DOTA-based prochelator, showed improved qualities as tumor targeted imaging probes in comparison to their monomeric analogues.Novel DOTA-based prochelator for divalent peptide vectorization: synthesis of dimeric bombesin analogues for multimodality tumor imaging and therapytext::journal::journal article::research article