Zhang, YanfengYin, QianYin, LichenMa, LiangTang, LiCheng, Jianjun2016-08-152016-08-152016-08-15201310.1002/anie.201300497https://infoscience.epfl.ch/handle/20.500.14299/128557Trigger happy: Trigger-responsive chain-shattering polymeric therapeutics (CSPTs) were prepared by condensation polymerization of a UV- or hydrogen peroxide-responsive domain and a drug as co-monomers. Drug release can be started and stopped by starting and stopping the trigger treatment. Chemotherapeutic-containing CSPTs showed trigger-responsive in vitro and in vivo antitumor efficacy.Chain-Shattering Polymeric Therapeutics with On-Demand Drug-Release Capabilitytext::journal::journal article::research article