Piredda, Gian FrancoHilbert, TomCanales-Rodrígez, Erick JorgePizzolato, MarcoMeuli, RetoPfeuffer, JosefThiran, Jean-PhilippeKober, Tobias2020-01-022020-01-022020-01-022019-05-01https://infoscience.epfl.ch/handle/20.500.14299/164316Impaired myelin plays a central role in a wide range of degenerative brain diseases. A method for non-invasive and in vivo assessment of myelin content within clinically acceptable acquisition times is thus desirable. In this work, a 3D multi-echo gradient and spin-echo (GRASE) sequence was accelerated with CAIPIRINHA to achieve high-resolution and whole-brain myelin imaging in less than ten minutes. Myelin water fraction (MWF) maps were derived from multi-echo GRASE data in a cohort of healthy subjects and values proved to be consistent with MWF maps computed from a conventional multi-echo spin-echo acquisition.text::conference output::conference poster not in proceedings