Juillerat, AlexandreKeppler, AntjeJohnsson, KaiGronemeier, ThomasGendreizig, SusanneBrecht, Andreas2015-09-222015-09-222015-09-222004https://infoscience.epfl.ch/handle/20.500.14299/118285The present invention relates to methods of transferring a label from suitable substrates to O6-alkylguanine-DNA alkyltransferase (AGT) fusion proteins, to suitable fusion proteins, to suitable variants of AGT, and to novel labelled fusion proteins obtained. A protein of interest is incorporated into an AGT fusion protein, the AGT fusion protein is contacted with an AGT substrate carrying a label, and the AGT fusion protein is detected and/or manipulated using the label in a system designed for recognising and/or handling the label.Protein labelling with o6-alkylguanine-dna alkyltransferasepatentUS2006292651ZA200502211JP2006501286CN1717496EP1546370KR20050049513AU2003267423CA2501061WO200403140432050143