Schmocker, AndreasPoupart, OrianePioletti, Dominique2019-12-052019-12-052019-12-052018https://infoscience.epfl.ch/handle/20.500.14299/163601A photopolymerizable bone filler material comprising a fluid polymeric material, a photoinitiator and a plurality of solid, polymeric optical fibers is disclosed, wherein said optical fibers are used for both illumination and reinforcement of the entire photopolymerized structure. In one embodiment, a mixture of PMMA and MMA is used as the fluid polymeric material. In one embodiment, the photoinitiator belongs to the bisacylphosphine oxide (BAPO) family, providing a complete, quick and reliable polymerization of a PMMA/MMA liquid bone cement upon application of a light of suitable wavelength. Contrary to other photoinitiators and chemically-similar compounds used in an experimental setting, the BAPO photoinitiator permits to obtain a polymerized bone cement which is mechanically robust and suitable for in vivo applications. Methods for using the developed fluid bone filler are also herein disclosed.patentJP2020500092EP3541440US2019275201CA3043849WO201809202957326286