Serrano, EloisaDe Nanteuil, FlorianWaser, Jerome2014-11-132014-11-132014-11-13201410.1055/s-0034-1378512https://infoscience.epfl.ch/handle/20.500.14299/108691WOS:000342570400014In this Letter, we describe the synthesis of new donor-acceptor substituted cyclopropanes bearing various imido groups and their use in [3+2]-annulation reactions. A sequence of palladium-catalyzed vinylation and rhodium-catalyzed cyclopropanation gave access to the required cyclopropanes in only two steps and high overall yields. The obtained compounds were used successfully in the tin-catalyzed [3+2] annulation with enol ethers to give cyclopentylamine derivatives in 22-95% yield.annulationcarbocycleshomogenous catalysisnitrogenring openingDiester-Substituted Aminocyclopropanes: Synthesis and Use in [3+2]-Annulation Reactionstext::journal::journal article::research article