Maerkl, Sebastian J.2008-12-242008-12-242008-12-24200910.1039/b819762hhttps://infoscience.epfl.ch/handle/20.500.14299/33024WOS:000266978200003Biology has always been a heavily technology limited field. Burgeoning fields such as systems biology require the development and implementation of new technologies, enabling high-throughput and high-fidelity measurements of large systems. Microfluidics promises to fulfil many of the requirements put forth. Here I will discuss the various approaches employed to date for performing high-throughput screening experiments on-chip, encompassing biochemical, biophysical, and cell-based assays.Protein Crystallization ConditionsLarge-Scale IntegrationActivated Cell SorterGene-ExpressionSingle-CellSystems BiologyNanoliter-ScaleSaccharomyces-CerevisiaeMultistep SynthesisPhase-BehaviorIntegration column: Microfluidic high-throughput screeningtext::journal::journal article::review article