Cristofari, G.Reichenbach, P.Regamey, P. O.Banfi, D.Chambon, MarcTurcatti, G.Lingner, J.2007-11-202007-11-202007-11-20200710.1038/nmeth1099https://infoscience.epfl.ch/handle/20.500.14299/14810WOS:00024977820002111274We designed a method termed Telospot to discover and characterize telomerase modulators as anticancer drugs or chemical biology tools. Telospot is based on a highly efficient human telomerase expression system and the detection of telomerase DNA reaction products in macroarray format. Telospot offers a highly scalable, cost- and time-effective alternative to presently available telomerase assays, which are limited by the requirement for PCR, telomerase purification or technologies not amenable to high throughput.Low- to high-throughput analysis of telomerase modulators with Telospottext::journal::journal article::research article