Bitbol, Anne-FlorencePeliti, L.Fournier, J. -B.2020-03-032020-03-032020-03-032011-0510.1140/epje/i2011-11053-4https://infoscience.epfl.ch/handle/20.500.14299/167048WOS:000290936900009We derive the expression of the stress tensor for one-and two-component lipid membranes with density and composition inhomogeneities. We first express the membrane stress tensor as a function of the free-energy density by means of the principle of virtual work. We then apply this general result to a monolayer model which is shown to be a local version of the area-difference elasticity (ADE) model. The resulting stress tensor expression generalizes the one associated with the Helfrich model, and can be specialized to obtain the one associated with the ADE model. Our stress tensor directly gives the force exchanged through a boundary in a monolayer with density and composition inhomogeneities. Besides, it yields the force density, which is also directly obtained in covariant formalism. We apply our results to study the forces induced in a membrane by a local perturbation.Bicontinuous Cubic PhasesLipid-BilayersProtein InteractionsThickness FluctuationsHydrophobic MismatchGramicidin ChannelsMembrane-ProteinSingle-ChannelChain-LengthIon-ChannelMembrane stress tensor in the presence of lipid density and composition inhomogeneitiestext::journal::journal article::research article