Li, H. Q.Bleriot, Y.Mallet, J. M.Rodriguez-Garcia, E.Vogel, P.Zhang, Y. M.Sinay, P.2005-11-092005-11-092005-11-09200510.1016/j.tetasy.2004.12.005https://infoscience.epfl.ch/handle/20.500.14299/219848WOS:0002270026000056057Eight new seven-membered ring iminoalditols, displaying an amino group and a hydroxymethyl group on the ring, have been synthesized from D-arabinose via epoxidation of a protected azacycloheptene and subsequent nucleophilic opening. Three of them show a potent glycosidase inhibition on amyloglucosidase and, to a lesser extend, on alpha-L-fucosidase. (C) 2004 Elsevier Ltd. All rights reserved.7-membered iminocyclitolsmimicking monosaccharidesbiologicalevaluationimino sugarsagentspolyhydroxyazepanesbindingring16-dideoxy-16-imino-d-glucitoltetrahydroxyazepanesNew 1-amino-1-deoxy- and 2-amino-2-deoxy-polyhydroxyazepanes: synthesis and inhibition of glycosidasestext::journal::journal article::research article