Ribes, DelphineParafita, J.Charrier, RémiMagara, F.Magistretti, PierreThiran, Jean-Philippe2011-04-292011-04-292011-04-29201110.1371/journal.pone.0014094https://infoscience.epfl.ch/handle/20.500.14299/66900In this article we introduce JULIDE, a software toolkit developed to perform the 3D reconstruction, intensity normalization, volume standardization by 3D image registration and voxel-wise statistical analysis of autoradiographs of mouse brain sections. This software tool has been developed in the open-source ITK software framework and is freely available under a GPL license. The article presents the complete image processing chain from raw data acquisition to 3D statistical group analysis. Results of the group comparison in the context of a study on spatial learning are shown as an illustration of the data that can be obtained with this tool.LTS5autoradiographytext::journal::journal article::research article