Stoll, T. S.Perregaux, C.Von Stockar, U.Marison, I. W.2006-02-272006-02-272006-02-271995https://infoscience.epfl.ch/handle/20.500.14299/225995WOS:A1995BF13G00080An IgA producing hybridoma cell line has been grown in various bioreactor systems, in serum-contg. and serum-free media. Bioreactors and media have been compared on the basis of product quantity (total IgA) and quality (activity, monomer/dimer/polymer ratios). IgA was produced in vitro with an activity similar to ascites fluid. The serum-free media was found to be better for such purposes. Prodn. in hollow fiber reactors resulted in high concns. of product, but with a lower activity fraction, possibly due to the formation of aggregates. [on SciFinder (R)]text::conference output::conference proceedings::conference paper