Insights into the Structure and Dynamics of Measles Virus Nucleocapsids by H-1-detected Solid-state NMR

Barbet-Massin, EmelineFelletti, MicheleSchneider, RobertJehle, StefanCommunie, GuillaumeMartinez, NicolasJensen, Malene RingkjobingRuigrok, Rob W. H.Emsley, LyndonLesage, AnneBlackledge, MartinPintacuda, Guido2015-01-082015-01-082015-01-08201410.1016/j.bpj.2014.05.048https://infoscience.epfl.ch/handle/20.500.14299/109947WOS:000340578100018H-1-detected solid-state nuclear magnetic resonance (NMR) experiments are recorded on both intact and trypsin-cleaved sedimented measles virus (MeV) nucleocapsids under ultra-fast magic-angle spinning. High-resolution H-1,N-15-fingerprints allow probing the degree of molecular order and flexibility of individual capsid proteins, providing an exciting atomic-scale complement to electro microscopy (EM) studies of the same systems.Insights into the Structure and Dynamics of Measles Virus Nucleocapsids by H-1-detected Solid-state NMRtext::journal::journal article::research article