Lefebvre, A.-M.Auwerx, J.Briggs, M.R.2009-04-212009-04-212009-04-211998https://infoscience.epfl.ch/handle/20.500.14299/37332Methods and compositions are provided for treating a host having a gastrointestinal (GI) disease by administering to the host a composition containing a pharmaceutically effective amount of a modulator of a Peroxisome Proliferator Activated Receptor (PPAR), particularly a modulator of PPAR gamma . Screening methods are also provided for identifying PPAR modulators which utilize cells derived from gastrointestinal tissue which express PPARspatentAU6773598WO984308121916159