Wei, Hai-LongPiou, TiffanyDufour, JérémyNeuville, LucZhu, Jieping2011-04-302011-04-302011-04-30201110.1021/ol2005243https://infoscience.epfl.ch/handle/20.500.14299/66927WOS:000289956700026Cyclisative carbo-iodination of N-alkyl-N-arylacrylamide derivatives (3) in the presence of PhI(OAc)2/I2 afforded functionalized 3-(iodomethyl)-3-substituted-indolin-2-ones (4) in good to excellent yields. With a suitably functionalized linear amide, spirooxindole 8 was prepared in a one-pot fashion via a sequence of iodo-arylation followed by an in situ base-promoted intramolecular SN2 reaction.IodocarbocyclizationoxindolespirooxindolehypovalentiodineIodo-Carbocyclization of Electron-Deficient Alkenes: Synthesis of Oxindoles and Spirooxindolestext::journal::journal article::research article