De Paolis, MichaeelBlankenstein, JoergBois-Choussy, MicheleZhu, Jieping2010-11-252010-11-252010-11-25200210.1021/ol025743zhttps://infoscience.epfl.ch/handle/20.500.14299/58505Simply mixing amino alc. I (R = substituent) and thiols in toluene and TFA provided the corresponding amino sulfide II in excellent chem. yield and diastereoselectivity. A double SN2 process initiated by O-5 participation of the neighboring N-carbamate group was advanced to explain the overall retention of configuration at the chiral benzylic center. [on SciFinder (R)]Stereoselective synthesis; Substitution reaction (N-carbamate-assisted stereoselective synthesis of chiral vicinal amino sulfides); Sulfides Role: SPN (Synthetic preparation)PREP (Preparation) (amino; N-carbamate-assisted stereoselective synthesis of chiral vicinal amino sulfides)stereoselective synthesis chiral vicinal amino sulfidetext::journal::journal article::research article