Dyson, PaulAnge, Wee2015-09-222015-09-222015-09-222007https://infoscience.epfl.ch/handle/20.500.14299/118294The present invention relates to organometallic compounds useful in the treatment of metastasis. The organometallic compounds comprise a ligand that is convalently bound to a bioactive compound, which is an inhibitor of a resistance pathway or a derivative thereof. Preferably, the organometallic compounds are half-sandwich ("piano-stool") compounds. The compounds of the present invention offer a high variability with respect to the bioactive compound and to the nature of the ligand bound to a central transition metal.patentEP2016085EP2016085US2015190362US9018199US2009312301EP2016085WO200712815837770371