Salcedo, AngelaNeuville, LucRondot, ChristopheRetailleau, PascalZhu, Jieping2010-11-252010-11-252010-11-25200810.1021/ol7029799https://infoscience.epfl.ch/handle/20.500.14299/58413A divergent and regiocontrolled Pd-catalyzed domino sequence involving an intramol. N-arylation and an intermol. Heck reaction has been developed, providing rapid access to functionalized benzodiazepine-2,5-diones, e.g. I. The starting materials were synthesized by the Ugi four-component reaction. An unprecedented X-ray structure of a bispalladacycle was documented. [on SciFinder (R)]Addition reaction catalysts (Ugi; prepn. of functionalized benzodiazepine-25-diones by Pd-catalyzed domino sequence involving Ugi four-component reactionintramol. N-arylationand an intermol. Heck reaction); Arylation; Arylation catalysts; Heck reaction; Heck reaction catalysts; Ugi reaction (prepn. of functionalized benzodiazepine-25-diones by Pd-catalyzed domino sequence involving Ugi four-component reactionintramol. N-arylationand an intermol. Heck reaction)benzodiazepinedione prepn; palladium catalyst Ugi reaction arylation Heck reaction; bispalladacycle prepn crystal structuretext::journal::journal article::research article