Muriel, BastianOrcel, UgoWaser, Jerome2017-09-052017-09-052017-09-05201710.1021/acs.orglett.7b01524https://infoscience.epfl.ch/handle/20.500.14299/140217WOS:000405358300055The selective palladium-catalyzed carboamination of allylic alcohols is reported on the basis of the use of an easily introduced trifluoroacetaldehyde-derived tether. Aminoalkynylation reactions were realized using alkynyl bromides and commercially available phosphine ligands. For aminoarylations, a new biaryl phosphine ligand, Fu-XPhos, was introduced to overcome a competitive Heck pathway. The carboamination products were obtained in high yields and diastereoselectivity. The tether could be easily removed to give value-added amino alcohol building blocks.text::journal::journal article::research article