Coste, GĂ©raldGerber-Lemaire, Sandrine2006-05-152006-05-152006-05-15200610.1002/ejoc.200600276https://infoscience.epfl.ch/handle/20.500.14299/230134WOS:0002404253000129237The asymmetric synthesis of long chain di- and tri-amino polyols is reported. The developed methodology is based on the functionalization of 3,3'-methylenebis{[6-(benzyloxy)methoxy]cyclohept-3-en-1-ol} derivatives that allows the selective introduction of amine moieties on defined positions of polyketide fragments. The versatile strategy disclosed here requires few purification steps and may generate a large panel of stereoisomers.aminopolyolspolyketidesselective protectionNew efficient synthesis of long chain di- and tri-aminopolyolstext::journal::journal article::research article