Luksys, GediminasSandi, Carmen2011-05-242011-05-242011-05-24201110.1016/j.conb.2011.03.003https://infoscience.epfl.ch/handle/20.500.14299/67801WOS:000294097100020Stress has complex effects on memory function that can vary depending on the type of information that is learned and in relation to inter-individual characteristics. Recent work has also shown that stress can switch performance between memory systems, biasing it toward habit in detriment of spatial or goal-directed strategies. In addition, novel synaptic mechanisms have been implicated in the effects of stress in plasticity and memory. Computational modeling is emerging as a useful approach to integrate and to ascertain neural and cognitive computations underlying different effects of stress in memory. Having provided novel explanations for the inverted-U-shaped relationship between stress and cognitive performance, model-based analysis studies can improve our understanding of diverse effects of stress in cognition and psychopathology.Decision-MakingIndividual-DifferencesRewardBehaviorHumansBrainNorepinephrineConsolidationExploitationHippocampustext::journal::journal article::research article