Steffen, FrankYoshihara, Hikari A. I.Mishkovsky, MorComment, ArnaudGruetter, Rolf2020-09-182020-09-182020-09-182017https://infoscience.epfl.ch/handle/20.500.14299/171764Hyperpolarized 2-keto[1-13C]isocaproate (KIC) provides a means to probe brain nitrogen homeostasis and to assess molecular signatures of tumors. The dynamic nuclear polarization process requires a free-radical polarizing agent, and samples are typically doped with persistent radicals. An alternative is to use photo-induced radicals of α-keto acids that recombine upon dissolution. [1-13C]KIC hyperpolarized with photo-induced radicals could be used to measure the alterations in amino acid metabolism that are linked to neurodegenerative diseases and cancer, and the aim of the present study is to identify the main features that influence the polarization dynamictext::conference output::conference poster not in proceedings