Baudouin, D.Van Kalkeren, H. A.Bornet, A.Vuichoud, B.Veyre, L.Cavailles, M.Schwarzwaelder, M.Liao, W. -C.Gajan, D.Bodenhausen, G.Emsley, L.Lesage, A.Jannin, S.Coperet, C.Thieuleux, C.2016-11-212016-11-212016-11-21201610.1039/c6sc02055khttps://infoscience.epfl.ch/handle/20.500.14299/131287WOS:000386228900033Hyperpolarization of metabolites by dissolution dynamic nuclear polarization (D-DNP) for MRI applications often requires fast and efficient removal of the radicals (polarizing agents). Ordered mesoporous SBA-15 silica materials containing homogeneously dispersed radicals, referred to as HYperPolarizing SOlids (HYPSOs), enable high polarization - P(H-1) = 50% at 1.2 K - and straightforward separation of the polarizing HYPSO material from the hyperpolarized solution by filtration. However, the one-dimensional tubular pores of SBA-15 type materials are not ideal for nuclear spin diffusion, which may limit efficient polarization. Here, we develop a generation of hyperpolarizing solids based on a SBA-16 structure with a network of pores interconnected in three dimensions, which allows a significant increase of polarization, i.e. P(H-1) = 63% at 1.2 K. This result illustrates how one can improve materials by combining a control of the incorporation of radicals with a better design of the porous network structures.text::journal::journal article::research article