Imbeault, MichaelTrono, Didier2014-12-302014-12-302014-12-30201410.1016/j.devcel.2014.10.019https://infoscience.epfl.ch/handle/20.500.14299/109692WOS:000344843000001Retroelements, constituting about 50% of the human genome, both contribute to its evolution and threaten its integrity and are thus silenced during development. Jacobs et al. (2014) identify sequence-specific KRAB-ZNF proteins that repress subsets of L1 and SVA retrotransposons in humans, highlighting the evolutionary interplay between retroelements and their hosts.As Time Goes by: KRABs Evolve to KAP Endogenous Retroelementstext::journal::journal article::research article