Gademann, KarlBethuel, Yann2006-11-222006-11-22200410.1002/anie.200453909https://infoscience.epfl.ch/handle/20.500.14299/235834A postulated biogenesis forms the basis for a synthetic route to the natural product anachelin H. Key steps include a tellurium-mediated, oxidative aza annulation and a Claisen condensation under mild conditions. Experiments with a model substrate indicate that it is likely that a catechol oxidase-type enzyme is involved in the biosynthesis of the anachelin chromophore.alkaloidsbiomimetic synthesesnatural productspeptidespolyketidestext::journal::journal article::research article