Tandem Photoredox and Copper-Catalyzed Decarboxylative C(sp3)–N Coupling of Anilines and Imines Using an Organic Photocatalyst

Barzanò, GuidoMao, RunzeGarreau, MarionWaser, JérômeHu, Xile2023-01-252023-01-252023-01-252020-06-2610.1021/acs.orglett.0c01769https://infoscience.epfl.ch/handle/20.500.14299/194297An organic photoredox catalyst, 4CzIPN, was used in combination with a copper catalyst, CuCl, to effect decarboxylative C(sp3)–N coupling. The coupling worked with both anilines and imines as nitrogen sources and could be used to prepare a variety of alkyl amines from readily available alkyl carboxylic acids.Tandem Photoredox and Copper-Catalyzed Decarboxylative C(sp3)–N Coupling of Anilines and Imines Using an Organic Photocatalysttext::journal::journal article::research article