Improved Carbon-Carbon Linking by Controlled Copper Catalysis

Fouquet, GerdSchlosser, Manfred2006-03-032006-03-032006-03-03197410.1002/anie.197400821https://infoscience.epfl.ch/handle/20.500.14299/226753Treatment of RO3SC6H4Me-4 with R1MgBr in THF over Li2CuCl4 at -78 Deg with slowly raising the temp. to room temp. gave, in good yields, the derivs. RR1 (R = e.g. Et, Ph, cyclohexyl, or octyl; R1 = Et, CMe3, Ph, cyclohexyl). [on SciFinder (R)]Grignard reaction catalysts (lithium chlorocupratefor org. bromides with tosylates); Grignard reaction (of org. bromides with tosylatesmechanism of catalytic)Grignard reaction catalyst chlorocuprate; lithium chlorocuprate catalyst Grignard; alkyl tosylate Grignard reactionImproved Carbon-Carbon Linking by Controlled Copper Catalysistext::journal::journal article::research article