Dagousset, GuillaumeErb, WilliamZhu, JiepingMasson, Géraldine2014-05-142014-05-142014-05-14201410.1021/ol500946whttps://infoscience.epfl.ch/handle/20.500.14299/103301WOS:000335491000065The reaction of anilines and phenylacetaldehydes in the presence of chiral phosphoric acid afforded optically active 1,2-trans, 2,3-cis 1,3-diaminotetralins in high yields with excellent diastereo- and enantioselectivities. The trans/cis product was readily isomerized to a trans/trans stereoisomer with no significant loss of enantiomeric purity.text::journal::journal article::research article