Rockel, S.Geertz, M.Hens, K.Deplancke, B.Maerkl, S. J.2013-05-172013-05-172013-05-17201310.1093/nar/gks1323https://infoscience.epfl.ch/handle/20.500.14299/92302WOS:000318062000002Mapping gene regulatory networks is a significant challenge in systems biology, yet only a few methods are currently capable of systems-level identification of transcription factors (TFs) that bind a specific regulatory element. We developed a microfluidic method for integrated systems-level interaction mapping of TF-DNA interactions, generating and interrogating an array of 423 full-length Drosophila TFs. With integrated systems-level interaction mapping, it is now possible to rapidly and quantitatively map gene regulatory networks of higher eukaryotes.text::journal::journal article::research article