Pettinari, RiccardoMarchetti, FabioPettinari, ClaudioPetrini, AgneseScopelliti, RosarioClavel, Catherine M.Dyson, Paul J.2015-02-202015-02-202015-02-20201410.1021/ic502274bhttps://infoscience.epfl.ch/handle/20.500.14299/111409WOS:000346544100051Novel ruthenium half-sandwich complexes containing (N,O)-bound pyrazolone-based beta-ketoamine ligands have been prepared, and the solid-state structures of one ligand and five complexes have been determined by single-crystal X-ray diffraction. Some of the complexes display moderate cytotoxicity toward the human ovarian cancer cell lines A2780 and A2780cisR, the latter line having acquired resistance to cisplatin.Synthesis, Structure, and Antiproliferative Activity of Ruthenium(II) Arene Complexes with N,O-Chelating Pyrazolone-Based beta-Ketoamine Ligandstext::journal::journal article::research article