A Gadolinium Complex Confined in Silica Nanoparticles as a Highly Efficient T1/T2 MRI Contrast Agent

Wartenberg, NicolasFries, PascalRaccurt, OlivierGuillermo, ArmelImbert, DanielMazzanti, Marinella2014-11-072014-11-072014-11-07201310.1002/chem.201300635https://infoscience.epfl.ch/handle/20.500.14299/108515WOS:000319139400011Gd in silica: Noncovalent confinement of a monoaqua Gd chelate into biocompatible silica nanoparticles (NPs; see figure) by a sol-gel method affords a new example of nanosized contrast agents with very high per-Gd relaxivities. Such NPs provide a route to highly efficient multimodal contrast agents. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.A Gadolinium Complex Confined in Silica Nanoparticles as a Highly Efficient T1/T2 MRI Contrast Agenttext::journal::journal article::research article