Qiao, LiangSartor, RomainGasilova, NataliaLu, YuTobolkina, ElenaLiu, BaohongGirault, Hubert H.2012-10-112012-10-112012-10-11201210.1021/ac301332khttps://infoscience.epfl.ch/handle/20.500.14299/86070WOS:000308255400022An electrostatic-spray ionization (ESTASI) method has been used for mass spectrometry (MS) analysis of samples deposited in or on an insulating substrate. The ionization is induced by a capacitive coupling between an electrode and the sample. In practice, a metallic electrode is placed close to but not in direct contact with the sample. Upon application of a high voltage pulse to the electrode, an electrostatic charging of the sample occurs leading to a bipolar spray pulse. When the voltage is positive, the bipolar spray pulse consists first of cations and then of anions. This method has been applied to a wide range of geometries to emit ions from samples in a silica capillary, in a disposable pipet tip, in a polymer microchannel, or from samples deposited as droplets on a polymer plate. Fractions from capillary electrophoresis were collected on a polymer plate for ESTASI MS analysis.text::journal::journal article::research article